Positive correlation between expression level of mitochondrial serine hydroxymethyltransferase and breast cancer grade
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چکیده
منابع مشابه
Positive correlation between expression level of mitochondrial serine hydroxymethyltransferase and breast cancer grade
Metabolic reprogramming plays an essential role in supporting the survival and proliferation of cancer cells. Serine hydroxymethyltransferase (SHMT) directs serine to the metabolism of one-carbon unit and the synthesis of thymidilate as a key factor in this metabolic shift. Although the mitochondrial isoform of SHMT (SHMT2) has been proven to be a crucial factor in the serine/glycine metabolism...
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ژورنال
عنوان ژورنال: OncoTargets and Therapy
سال: 2015
ISSN: 1178-6930
DOI: 10.2147/ott.s82433